双侧面瘫的影响因素及其预后分析

Retrospective analysis of influencing factors and prognosis of bilateral facial paralysis

摘要:

目的 分析双侧面瘫病因学，探讨影响预后的相关因素。方法 选取2010 年1 月-2016 年1 月 于本院治疗的33 例出现双侧面瘫的患者，回顾性分析性别、年龄、发病机制及是否使用激素、丙球治疗 与3 个月后双侧面瘫预后的相关性。结果 急性吉兰- 巴雷综合征（GBS）患者20 例，发生率60.6%。两 组患者早期是否使用激素有差异（P <0.05），患者早期使用激素与双侧面瘫3 个月预后呈正相关（P <0.05）。 结论 双侧面瘫大多数情况下是某一种系统性疾病的首发症状，最常见病因是急性GBS。在诊断特发性面神 经麻痹前，需完善相关检查，进行鉴别诊断。早期使用激素治疗会改善患者预后。

Abstract:

Objective To analyze the etiology and explore the factors influencing prognosis of bilateral facial paralysis. Methods A retrospective study was designed. The study participants were 33 patients with diagnosis of bilateral facial paralysis in our hospital between January 2010 to January 2016. And the correlations of gender, age, pathogenesis, hormone usage and immunoglobulin treatment with the prognosis of bilateral facial paralysis after 3 months were determined. Results Of the 33 patients with bilateral facial paralysis, 20 had Guillain-Barré syndrome, the incidence was 60.6%. The early use of hormone was positively associated with the prognosis of bilateral facial paralysis after 3 months (P < 0.05). Conclusions In most cases, bilateral facial paralysis is likely to be one or the first symptom of systemic diseases. Guillain-Barré syndrome is the most common cause. Before the diagnosis of idiopathic facial palsy, it is neccesary to finish the relevant examinations and conduct the differential diagnosis. Early use of hormone therapy may improve the prognosis of the patients.