颅内压监测并发中枢神经系统感染因素分析

Analysis of factors associated with intracranial pressure monitoring complicated with central nervous system infection

摘要:

目的 探讨有创颅内压监测患者并发中枢神经系统感染的独立危险因素。方法 收集2016 年 1 月-2017 年3 月该院收治的行有创颅内压监测患者60 例，其中并发中枢神经系统感染患者16 例（感染组）， 通过问卷调查方法收集患者基本资料、手术情况及术后并发症发生情况，多因素Logistic 回归分析有创颅内 压监测患者并发中枢神经系统感染的独立危险因素。结果 感染组与非感染组患者在年龄、性别、急诊手术、 电解质、血糖、疾病类型、手术时间、术后GCS 评分比较，差异无统计学意义（P >0.05）；两组患者在引 流管位置、引流管留置时间、探头位置、探头留置时间及并发症比较，差异有统计学意义（P <0.05）。多因 素Logistic 回归分析结果表明，探头位置为有创性颅内压监测发生中枢神经系统感染的保护因素[Ol ^ R=0.101 （95%CI：0.003，1.246）]，并发症为有创性颅内压监测发生中枢神经系统感染的危险因素[Ol ^ R=5.894（95%CI： 1.256，6.775）]。结论 探头位置、并发症为有创性颅内压监测发生中枢神经系统感染的独立危险因素。

Abstract:

Objective To investigate the independent risk factors of central nervous system infection in patients with invasive intracranial pressure monitoring. Methods From January 2016 to March 2017, 60 cases of patients having invasive intracranial pressure monitoring were treated in our hospital, including 16 patients with central nervous system infection (infection group). Basic information, surgical condtion and postoperative complications of the patients were collected through questionnaire survey. Multivariate logistic regression analysis was used to analyze the independent risk factors of central nervous system infection in the patients with invasive intracranial pressure monitoring. Results There was no significant difference in age, gender, emergency surgery, electrolytes, glucose, type of disease, operative time or GCS score between the infection group and the non-infection group (P > 0.05). The drainage tube position, drainage tube indwelling time, probe position, probe retention time and complications were statistically different between the two groups (P < 0.05). Multivariate logistic regression analysis showed that the position of the probe was the protective factor of central nervous system infection during invasive intracranial pressure monitoring [Ol ^ R = 0.101 (95% CI: 0.003,1.246)], while complications were the risk factors [Ol ^ R = 5.894 (95% CI: 1.256, 6.775)]. Conclusions Probe position and complications were independent risk factors of central nervous system infection during invasive detection of intracranial pressure.