血液营养指标预测老年粗隆间骨折术后1 年的死亡率

Prediction of one-year mortality after operation of elderly intertrochanteric fracture via blood nutrition indexes

摘要:

目的 回顾性分析血液营养指标对预测老年粗隆间骨折患者术后1 年死亡率的价值。方法 选取 2012 年1 月-2016 年1 月99 例年龄>65 岁，采用髓内钉手术治疗的粗隆间骨折患者。分析患者的性别、年龄、 入院血清白蛋白、总蛋白、球蛋白、前白蛋白、淋巴细胞计数（TLC）、血红蛋白、血清钾及钙等因素。手术后 随访1 年，随访患者生存情况。结果 99 例患者，术后随访1 年内死亡35 例。性别比较无差异（P >0.05）； 男女患者血液参数和淋巴细胞计数比较，差异无统计学意义（P >0.05）；男女的年龄、白蛋白含量及血红蛋白含 量比较，差异有统计学意义（P <0.05）。多因素线性回归分析显示，年龄和血红蛋白含量是预测术后1 年死亡 率的影响因素。结论 营养指标对粗隆间骨折患者的术后1 年死亡率有预测价值，年龄、血红蛋白及白蛋白对 死亡率有影响。

Abstract:

Objectives To retrospectively analyze the value of blood nutrition indexes in predicting the oneyear mortality rate after operation of elderly intertrochanteric fracture. Method A total of 99 patients over 65 years old who underwent intramedullary nailing with intertrochanteric fracture were selected from January 2012 to January 2016. Factors including gender, age, admission serum albumin, total protein, globulin, prealbumin, lymphocyte count (TLC), hemoglobin, serum potassium and calcium were analyzed. Survival of the patients were followed up one year after operation. Result Thirty-five of them were dead within one year after operation.There were no differences in gender (P > 0.05) and in blood parameters and lymphocyte count between male and female patients (P > 0.05). There were statistical differences in age, albumin and hemoglobin between male and female patients (P < 0.05). Further multivariate linear regression analysis was used to determine age (Ol ^ R: 0.911, 95% CI: 0.850, 0.977, P < 0.05) and hemoglobin (Ol ^ R: 1.030, 95% CI: 1.005, 1.056, P < 0.05) as factors in predicting one-year mortality after operation. Conclusion Nutritional indicators have predictive value for one-year mortality after intertrochanteric fracture; age, hemoglobin and albumin are significant to mortality rate.