肿瘤化疗患者焦虑和抑郁情绪与应对方式的关系研究

Analysis of cancer-related anxiety and depression induced by chemotherapy

摘要:

目的 探讨肿瘤化疗患者的焦虑、抑郁情绪及不同应对方式对焦虑、抑郁的影响。方法 选取 2016 年12 月-2017 年2 月4 所省、市级医院的339 位肿瘤化疗患者为研究对象，分析研究肿瘤化疗患者的焦 虑、抑郁状况与其应对方式的关系。结果 42.2% 的化疗患者存在焦虑情绪，43.1% 的化疗患者存在抑郁情绪， 30.7% 的患者两种情绪皆有。肿瘤化疗患者焦虑、抑郁得分均高于常模（P <0.05）；面对得分低于国内常模 （P <0.05），而回避和屈服得分均高于国内常模（P <0.05）。焦虑与屈服呈正相关（P <0.05）；抑郁与面对呈负 相关（P <0.05），与回避、屈服呈正相关（P <0.05）。多元逐步回归分析显示，医疗保障、职业及屈服是焦虑 的影响因素（P <0.05）；职业、屈服、面对及回避是焦虑的影响因素（P <0.05）。结论 肿瘤化疗患者存在较为 普遍的焦虑、抑郁情绪，这与其应对方式有一定的关系，尤其是屈服的应对方式对焦虑、抑郁情绪的产生具有 重要影响。

Abstract:

Objective To explore the incidence of anxiety and depression induced by chemotherapy and their correlation with different coping modes. Methods A total of 339 cancer patients during the chemotherapy were interviewed from 4 hospitals. T-test, single factor analysis of variance, partial correlation and regression analysis were carried out to study the relationship of anxiety and depression with coping modes. Results Exactly 42.2% of patients had anxiety, 43.1% of patients had depression and 30.7% of patients had both issues. Anxiety score and depression score in chemotherapy patients were significantly higher than standard norm (P < 0.05). Face score was lower while the yield and avoidance score were higher significantly than national norm (P < 0.05). Anxiety was positively related with yield (P < 0.05). Depression was negatively related with facing while positively relatedwith yield and avoidance (P < 0.05). Multivariate stepwise regression analysis showed that health care, occupation and yield were independent risk factors for anxiety (P < 0.05). Occupation, yield, faceand avoidance were independent risk factors for anxiety (P < 0.05). Conclusions Anxiety and depression in cancer patients during chemotherapy is prevailing. Coping mode of surrender closely affects incidence of chemotherapy-inducedanxiety and depression.