Abstract:Objective To assess the feasibility and advantage of iterative reconstruction (IR) in low-dose CT (LDCT) scanning of cerebral hemorrhage. Methods Totally 90 adult patients with cerebral hemorrhage in a week who needed CT re-scanning were chosen at random for a study of IR in LDCT. They were divided into three groups respectively with radiation dose levels of 100 mAs, 150 mAs and 200 mAs for head CT scanning. Then, IR and filter back projection (FBP) reconstructionwere used. Paired sample t test was applied to evaluate the difference in the image quality between different reconstruction modes in different dose groups. Results For review cases with cerebral hemorrhage: there were statistically significant differences in image noise level between the two reconstructed groups in each dose group (P < 0.05); between 100 mAs dose and 200 mAs dose groups of IR, there were no significant differences in image quality score (P > 0.05), but there was significant difference in image noise level (P < 0.05); between 100 mAs dose and 200 mAs dose groups of FBP, there were significant differences in image quality score and image noise level (P < 0.05); between 150 mAs dose and 200 mAs dose groups of FBP, there was no significant difference in image quality score (P > 0.05), but there was significant difference in image noise level (P < 0.05). Conclusions IR algorithm can achieve lower image noise level than FBP in the same dose manner of head CT scanning; IR has lower radiation dose than FBP with the same image subjective score. IR has the advantage of lower radiation dose than FBP (100 mAs versus 150 mAs ) on head CT re-scanning of patients with cerebral hemorrhage.