阴道3D-CPA 诊断绝经后子宫内膜 良、恶性病变的准确性研究

Diagnostic value of vaginal three-dimensional Doppler ultrasonography in endometrial disease

摘要:

目的 探讨阴道三维彩色能量多普勒超声（3D-CPA）诊断绝经后妇女子宫内膜疾病的准确性和 对内镜电切术的指导价值。方法 选取110 例绝经后患有子宫内膜疾病患者为研究对象。根据患者病理组织学 检验结果，分为子宫内膜病变良性组和恶性组。分析阴道3D-CPA 诊断绝经后子宫内膜疾病的准确性。结 果 恶性组各项超声参数、血流参数及微血管密度（MVD）值与良性组比较，差异有统计学意义（P <0.05）； 不同分期患者的各项超声参数差异无统计学意义（P >0.05），但晚期患者的MVD 数值高于Ⅰ期与Ⅱ期患 者，且Ⅱ期患者高于Ⅰ期（P <0.05）；阴道3D-CPA 的特异性和敏感性值均相对较高。结论 阴道3DCPA 鉴别绝经后子宫内膜疾病临床诊断效果好，对内镜电切术的治疗具有临床指导价值。

Abstract:

Objective To investigate the diagnostic accuracy of vaginal three-dimensional Doppler ultrasonography (3D-CPA) in endometrial disease of female patients in postmenopausal state. Methods A total of 110 patients with endometriosis were selected in this study. Patients were divided into 2 groups based on histopathological examination: benign group and malignant group. 3D-CPA was performed in each case. Results The ultrasonographic parameters, blood flow parameters and microvessel density (MVD) in malignant group were significantly different from those in the benign group (P < 0.05). No significant difference in the ultrasonographic parameters among various stages was founded (P > 0.05). MVD of patients with advanced stage was significantly increased compared with inferior stage. 3D-CPA results suggested that it could specifically recognize patients with malignant patients. Conclusion 3D-CPA is worthy for clinical application in screening patients with malignant endometrial disease with high specificity and sensitivity.