多排螺旋CT 图像半自动分割技术对北方健康 人群腹部脂肪分布的综合分析

Comprehensive analysis of abdominal fat distribution in healthy northerners by semi-automatic segmentation of multi-slice CT images

摘要:

目的 应用多排螺旋CT（MSCT）评价健康北方人腹部脂肪分布情况，并分析其与年龄和腰围（WC） 的相关性。方法 应用MSCT 图像半自动分割技术测量287 例健康北方人脐平面的腹腔内脂肪面积（VA）、腹 壁皮下脂肪面积（SA）、VA/（VA+SA）、腰围（WC），将所有人按不同年龄和性别分组，并进行统计分析。 结果 男性VA 高于女性（P <0.05），女性SA 高于男性（P <0.05）。男性VA、女性VA、女性VA/VA+SA 随年 龄增长而增长（P <0.05），男性VA/VA+SA 在60 岁前随年龄增长而增长（P <0.05），但主要是20 ～ 40 岁组， 与其他各组差异有统计学意义（P <0.05）。男性和女性VA 与WC、年龄均呈正相关（P <0.05）；男性和女性 SA 与WC 均呈正相关（P <0.05），与年龄均不相关（P >0.05）。结论 MSCT 图像半自动分割技术测量腹部脂 肪含量可行；北方人群腹部脂肪分布在不同年龄、性别组中存在差异，腹部脂肪含量与年龄和WC 存在一定 相关。

Abstract:

Objective To evaluate the abdominal fat distribution characteristics of healthy northerners and its correlations with age and waist circumference using multi-slice CT. Methods Two hundreds and eighty-seven healthy northerners were enrolled in this study, and their CT images were obtained by multi-slice CT. The visceral adipose area (VA) and subcutaneous adipose area (SA), VA/(SA+VA), waist circumference (WC) in the navel plane were calculated by semi-automatic segmentation technology. All subjects were grouped according to their age and gender, then analyzed statistically. Results VA of male was higher than that of female (P < 0.05), while SA of male was lower than that of female (P < 0.05). VA and VA/ (VA+SA) of female increased with age (P < 0.05); and VA/ (VA+SA) of male increased with age before the age of 60 years (P < 0.05). VA/ (VA+SA) between the group of 20-40 years old and other groups was statistically different (P < 0.05). VA was positively correlated with WC and age (P < 0.05). SA was positively correlated with WC (P < 0.05). However, SA was not related to age (P > 0.05). Conclusions The semi-automatic segmentation technology on multi-slice CT images is a reliable tool in assessing abdominal fat content. There are significant differences in abdominal fat distribution among the northerners of different age and genders, and abdominal fat distribution has certain correlations with age and WC.