Abstract:Objective To compare the analgesic effect of ultrasound-guided fascia iliaca compartment nerve block (FICNB) and adductor canal block(ACB) in analgesia for elderly patients after knee replacement. Methods A total of 120 elderly patients undergoing knee replacement under general anesthesia were randomly divided into group A and group B with 60 cases in each group. Both group were given nerve block intervention 30 min before surgery. Group A were given ultrasound-guided FICNB while group B were given ACB. The effective rates of sensory block in different regions, resting and active visual analogue scores (VAS), muscle strength of quadriceps femoris and adverse reactions were compared between the two groups. Results The effective rates of lateral femoral cutaneous nerve and obturator nerve sensory block in group A 10 min, 20 min and 30 min after nerve block were significantly higher than those in group B (P < 0.05). The resting and active VAS scores of group A 2 h, 6 h, 12 h, 24 h and 48 h after surgery were significantly lower than those of group B (P < 0.05). The muscle strength of quadriceps femoris of group A 24 h after surgery was significantly smaller than that of group B (P < 0.05). There were no significant differences between the two groups in the muscle strength of quadriceps femoris and the incidence of adverse drug reactions 48 h after operation (P > 0.05). Conclusion Compared with adductor canal block, the analgesic effect of ultrasound-guided FICNB is more significant in the elderly after knee replacement. Though the effect of the later on muscle strength of quadriceps femoris is relatively greater 24 h after surgery, the effect decreases 48 h after surgery, it is recommended to choose the appropriate nerve block depending on the situation.