RetCam 3 筛查早产儿视网膜病变的 临床资料分析

Analysis of clinical data of RetCam3 screening for retinopathy of prematurity

摘要:

目的 应用眼科广域数字成像系统（RetCam 3）筛查早产儿眼底，分析筛查结果和发病特点。方法 回顾性分析该院2014 年2 月-2016 年2 月采用RetCam 3 筛查的早产儿152 例304 眼，对其中出现早产儿视 网膜病变（ROP）的43 眼进行综合分析。结果 在152 例（304 眼）早产儿以RetCam 3 检出各期ROP 43 眼（43/304），诊断为ROP Ⅰ期者33 眼（33/304），Ⅱ期者6 眼（6/304），Ⅲ期者4 眼（4/304）。本组病例中 未检出ROP Ⅳ期和Ⅴ期。双眼发病者与单眼发病者比较，双胎发病率与单胎发病率比较，均差异有统计学意 义（P <0.05）, 双眼发病者高于单眼发病者，双胎发病率高于单胎。男女、珍贵儿和自然儿之间ROP 发病率 比较，差异无统计学意义（P >0.05）。ROP 自然转归率达90%（39/43）。结论 要重视对早产儿视网膜病的筛查， 尤其双胎儿的眼底筛查，如果出现单眼发病，一定要详细检查和追踪另眼发病情况。应用RetCam 3 筛查早产 儿视网膜病变，尽可能早发现早产儿眼部异常，尽可能早治疗，减少儿童低视力和盲。

Abstract:

Objective To analyze the results and clinical characteristics of RetCam3 screening for retinopathy of prematurity (ROP). Methods This retrospective study included 152 cases (304 eyes) of premature infants who used RetCam 3 screening from February 2014 to February 2016. Among them 43 eyes suffered from ROP. Results In the 43 eyes (43/304) who had ROP, 33 eyes were diagnosed as stage I ROP, 6 eyes were stage II ROP, 4 eyes were stage III ROP. There was no stage IV or V ROP. The incidence of binocular ROP was significantly higher than that of monocular ROP (P < 0.05), the incidence of ROP in twins was higher than that in single babies (P < 0.05). There was no significant difference in ROP incidence between boys and girls, or between test-tube babies and natural babies (P > 0.05). 90% of ROP achieved normal retina without treatment. Conclusions Early inspection using RetCam3 screening, early detection and early treatment are of importance in preventing blinding caused by retinopathy of prematurity.