4 148 例输血患者红细胞输注无效的调查分析

Investigation and analysis of invalid red blood cell transfusion in 4,148 cases of blood cell transfusion

摘要:

目的 对临床红细胞输注无效患者进行回顾性分析，并就其影响因素提出相应的临床对策。 方法 选取2015 年5 月-2016 年5 月在湘雅医院行红细胞输注的4 148 例患者，患者输注红细胞后24 h 内复 查血红蛋白（Hb），与输血前比较，若Hb 未达到预期值，则视为红细胞无效输注，并对调查结果及相关因素 进行统计学分析。结果 医院总无效输血率为12.01%，血液内科无效输血率最高为21.25%，差异有统计学意 义（P <0.05）。红细胞输注效果与性别、年龄、输血次数有关，女性患者无效输血率高于男性患者（P <0.05）； 输血次数越多，无效输血率越高（P <0.05）；患者年龄越大，无效输血率越高（P <0.05）；血液病患者发生无 效输血率高于非血液病患者（P <0.05）。结论 医务人员应重视患者红细胞输血效果，及时采取相应措施，确 保临床输血疗效，做到合理使用血液资源。

Abstract:

Objective To investigate the invalid transfusion of red blood cells (RBCs) and its influencing factors, and put forward the corresponding clinical countermeasures. Methods Totally 4,148 cases of RBC transfusion in Xiangya Hospital from May 2015 to May 2016 were analyzed by a retrospective study. Hemoglobin (Hb) was measured within 24 hours after RBC transfusion. Compared with pre-transfusion, if hemoglobin did not reach the expected value, the RBC transfusion would be regarded as invalid transfusion. The influencing factors of invalid RBC transfusion were then statistically analyzed. Results The invalid RBC transfusion ratio of Xiangya Hospital was 12.01%, and the department with the highest invalid RBC transfusion ratio was Hematology Department with ratio of 21.25% (P < 0.05). The influencing factors of invalid RBC transfusion were gender, age and the number of transfusion. The female patients had a higher invalid RBC transfusion ratio compared to the male patients (P < 0.05). Larger number of transfusion and older age of patients indicated the higher possibility of invalid RBC transfusion (P < 0.05). The rate of invalid RBC transfusion in the patients with hematologic diseases was higher than that in non-hematologic patients (P < 0.05). Conclusions Attention should be paid to the effect of RBC transfusion in patients, and corresponding measures should be taken timely to ensure the efficacy of clinical blood transfusion.