不同偏头痛亚型与平衡障碍严重程度的关系

Relationships of different migraine subtypes and severity of balance disorder

摘要:

目的 探讨先兆性偏头痛、无先兆性偏头痛、慢性偏头痛患者与平衡功能障碍严重程度的关系。 方法 按照头痛疾患的国际诊断标准，选取偏头痛患者203 例。其中，先兆性偏头痛68 例，无先兆性偏头痛 73 例，慢性偏头痛62 例。分析3 种偏头痛亚型患者的临床资料和平衡障碍严重程度。采用Logistic 回归分析 平衡严重程度指标与3 种偏头痛亚型的关系。结果 多因素Logistic 回归分析结果显示，移动速度[Ol ^ R=2.96 （95%CI ：1.13，9.32）P =0.021]、方向控制[Ol ^ R=1.47（95%CI ：1.03，3.38）P =0.046] 是影响先兆性偏头痛患 者平衡功能障碍的重要因素；移动速度[Ol ^ R=3.76（95%CI ：1.21，9.28）P =0.042]、步宽[Ol ^ R=2.45（95%CI ： 1.73，6.74）P =0.009] 是影响无先兆性偏头痛平衡功能障碍的重要因素；移动速度[Ol ^ R=3.02（95%CI ：1.23， 8.96），P =0.000]，最大位移[Ol ^ R=1.59（95%CI ：1.22，3.67），P =0.043]，平均反应时间[Ol ^ R=1.89（95%CI ： 1.48，5.35），P =0.041] 是影响慢性偏头痛患者平衡功能障碍的重要因素。结论 不同偏头痛亚型患者存在轻 度或持续加重的平衡功能障碍，其中移动速度是影响先兆性偏头痛、无先兆性偏头痛和慢性偏头痛患者平衡 功能障碍的重要因素。

Abstract:

Objective To explore the relationships of migraine with aura, migraine without aura and chronic migraine with the severity of balance dysfunction. Methods According to the international diagnostic criteria of headache, 203 cases of migraine were selected and identified. Among them, 68 had migraine with aura, 73 had migraine without aura and 62 had chronic migraine. The clinical data of the three migraine subtypes and the severity of balance dysfunction were analyzed. And the relationships of the three migraine subtypes with the severity of balance dysfunction were analyzed by logistic regression. Results Multivariate logistic regression analysis showed that rate of movement [Ol ^ R = 2.96 (95% CI: 1.13, 9.32), P < 0.05] and direction control [Ol ^ R = 1.47 (95% CI: 1.03, 3.38), P < 0.05] were the important factors affecting the balance dysfunction of the patients with aura migraine; step width [Ol ^ R = 2.45 (95% CI: 1.73, 6.74), P < 0.05] and moving speed [Ol ^ R = 3.76 (95% CI: 1.21, 9.28), P < 0.05] were the important factors affecting the balance dysfunction of the patients with non-aura migraine; moving speed [Ol ^ R = 3.02 (95% CI: 1.23, 8.96), P < 0.05], maximal displacement [Ol ^ R = 1.59 (95% CI: 1.22, 3.67), P < 0.05] and mean response time [Ol ^ R = 1.89 (95% CI: 1.48, 5.35), P < 0.05] were the important factors affecting the balance dysfunction of the patients with chronic migraine. Conclusions Patients with different migraine subtypes have mild or continuously aggravated balance dysfunction, in which the velocity of movement is an important factor that affects the balance dysfunction of the patients with aura migraine, non-aura migraine and chronic migraine.