糖尿病合并急性心力衰竭的危险因素研究

Risk factors for type 2 diabetic patients complicated with acute heart failure

摘要:

目的 探究糖尿病（DM）合并急性心力衰竭（AHF）的危险因素。方法 收集AHF 患者196 例， 将60 例合并2 型糖尿病（T2DM）患者作为DM 组；136 例未合并DM 作为NDM 组。比较两组心功能、 肝功能、肾功能、血脂及红细胞系统指标。结果 两组年龄、抽烟≥ 10 年、心功能分级、合并高血压（HBP）、 合并高脂血症（HLP）、肌酐（Cr）、总胆固醇（TC）、三酰甘油（TG）、低密度脂蛋白胆固醇（LDL-C 及 红细胞平均体积（MCV）比较，差异有统计学意义（P <0.05）。多因素Logistics 回归分析显示，HLP、TC 及 LDL-C 为AHF 合并DM 的危险因素（P <0.05）。结论 HLP、TC 及LDL-C 与AHF 合并DM 的发生、发 展有密切关系，其增加AHF 合并DM 的风险。

Abstract:

Objective To investigate the risk factors for Diabetes Mellitus (DM) patients complicated with acute heart failure (AHF). Methods A total of 60 AHF patients complicated with Type 2 Diabetes Mellitus (T2DM) and 136 T2DM patients were involved in this study. Indexes of cardiac function, liver function, renal function, blood lipid and erythrocyte system were recorded. Results Age, smoking for more than 10 years, heart function, High Blood Pressure, Hyperlipidemia (HLP), Creatinine, Total Cholesterol (TC), Total Triglyceride, Low Density Lipoprotein Cholesterol (LDL-C), Mean Corpuscular Volume, Mean Corpuscular Hemoglobin, Mean Corpuscular Hemoglobin Concentration, Red Cell Distribution Width Standard Deviation, and Rend Cell Distribution Width-Coefficient of Variation were differently distributed in two groups. Multivariate Factor Logistics Regression Analysis suggested that HLP, TC and LDL-C were risk factor for development of AFH in DM patients. Conclusion Increased levels of HLP, TC and LDL-C enhance incidence of AHF in DM patients.