宫颈癌患者术后盆底功能障碍性疾病的 危险因素分析

Risk factors of postoperative pelvic floor dysfunction in patients with cervical cancer

摘要:

目的 探究宫颈癌患者术后盆底功能障碍性疾病的危险因素。方法 回顾该院收治的因宫颈癌和 子宫良性病变行子宫全切除的114 例患者作为研究对象，并将其分为宫颈癌组和对照组，每组各57 例。收集 患者一般资料、宫颈癌治疗情况、围术期情况及术后情况，统计宫颈癌患者治疗后盆底功能情况。结果 宫颈 癌患者的手术时间、留置尿管时间、住院时间长于对照组，术中出血量多于对照组（P <0.05）；宫颈癌组I 类肌 纤维力级别及疲劳度、Ⅱ类肌纤维力级别及疲劳度均短于对照组（P <0.05）；宫颈癌组中，发生PFD 共计37 例（64.9%），年龄>45 岁、便秘、分娩次数≥ 2 次，术后时间≥ 12 个月、导管留置时间≥ 7 d 及绝经患者盆 底功能障碍性疾病（PFD）发生率提高（P <0.05）。结论 年龄、便秘、分娩次数、尿管留置时间及绝经可能 是宫颈癌患者术后PFD 的危险因素。

Abstract:

Objective To investigate the risk factors of postoperative pelvic floor dysfunction (PFD) in patients with cervical cancer. Methods The patients undergoing total hysterectomy due to cervical cancer or benign uterus diseases were selected in this study. General clinic information, therapeutic interventions of patients and perioperative recovery status were recorded. Results Patients in cancer group experienced dramatic increase in operation time, indwelling of catheter, hospitalization time and intraoperative blood loss compared with those in benign disease group (P < 0.05). Grade and fatigue of class I and class II muscle fiber in cancer group were significantly worsened compared with benign group (P < 0.05). Totally 37 out of 57 cases of cervical cancer patients (64.9%) suffered from PFD. Age larger than 45 years old, constipation, times of delivery greater than 2 times, postoperative timelarger than12 months, catheter retention time more than 7 d and post menopause were closely associated with incidence of PFD (P < 0.05). Conclusions Age, constipation, number of childbirth, catheter retention time and postmenopausal women are the risk factors of pelvic floor dysfunction after cervical cancer surgery.