Abstract:Objective To observe the results of tear film stability and lacrimal secretion of undergraduates in winter vacation and summer vacation. Methods Totally 263 college students (263 right eyes) who had dry eye examination during winter and summer vacations were selected, and divided into a winter vacation group (125 eyes) and a summer vacation group (138 eyes). In both groups the first noninvasive tear film break-up time (NITBUTf), the average noninvasive tear film break-up time (NITBUTav), the inferior tear meniscus height (ITMH) and Schirmer Ⅰ test result were observed. Results NITBUTf and NITBUTav and ITMH were significantly different between the two groups (P < 0.05). Schirmer Ⅰ test result was not statistically different between the two groups (P > 0.05). Conclusions The dry eye examination results of undergraduates are different in winter vacation and summer vacation in central China. The stability of tear film in summer vacation is better than that in winter vacation, and the inferior tear meniscus height is similar. Schirmer I test result has no difference in winter vacation and summer vacation.