Objective To investigate the diagnostic value of conventional ultrasonography combined with elastography and mammography in multimodal imaging of triple-negative breast carcinoma. Methods The manifestations of conventional ultrasonogram, elastogram and mammogram in 63 cases of triple-negative breast carcinoma were analyzed retrospectively. The clinical value of ultrasonography combined with elastography and mammography in diagnosis of triple-negative breast carcinoma was compared. The accuracy of combined diagnosis for triple-negative breast carcinoma was analyzed. Results The accordance rates of ultrasonography combined with elastography, mammography and their combination for diagnosis of thriple-negative breast cancer were 84.1%, 77.80% and 92.1% respectively. Compared with mammography, the diagnosis accuracy of ultrasonography in thriple-negative breast cancer was higher. When the two images were combined, the diagnostic accuracy for the thriple-negative breast cancer was higher than that of single use of ultrasonography or mammography. Conclusions Multimodal imaging is helpful to improve the diagnostic rate of triple-negative breast carcinoma.