超声造影评估不同亚型功能性消化不良 患者胃排空的价值

Evaluation of gastric emptying in patients with different subtypes of functional dyspepsia by contrast-enhanced angiography

摘要:

目的 探究超声造影评估不同亚型功能性消化不良（FD）患者胃排空的价值。方法 选择四川 省人民医院东院收治的FD 患者188 例，分为上腹痛综合征（EPS）组和餐后不适综合征（PDS）组，同时选 择85 例健康体检者作为对照组。观察禁食、0、30、60、90 和120 min 时全胃腔容积（TGCV）、胃排空率 的变化。比较患者治疗前与治疗后120 min 的胃排空率差异。结果 两组FD 患者超声与核素扫描的120 min 平均胃排空率比较，差异无统计学意义（P >0.05）。3 组不同时间点的TGCV 和胃排空率比较，差异有统计 学意义（P <0.05），3 组患者TGCV 胃排空率比较，差异有统计学意义（P <0.05），3 组患者TGCV、胃排空 率变化趋势比较，差异有统计学意义（P <0.05）。EPS 组和PDS 组患者治疗前后的胃排空率比较，差异有统 计学意义（P <0.05）。结论 超声造影可以客观地评估FD 患者疗效，传统治疗方案对PDS 患者的疗效优于 EPS 患者。

Abstract:

Objective To evaluate the value of contrast-enhanced ultrasonography in assessing gastric emptying in patients with different subtypes of functional dyspepsia (FD). Methods A total of 188 FD patients admitted to Eastern Hospital of Sichuan Provincial People’s Hospital were enrolled. There were 96 patients with upper epigastric pain syndrome (EPS group) and 92 patients with postprandial discomfort syndrome (PDS group). Meanwhile, 85 healthy subjects were enrolled as the control group. The changes of total gastric cavity volume (TGCV) and gastric emptying rate were observed during fasting, at 0, 30, 60, 90 and 120 min after taking contrast medium. The difference in 120-min gastric emptying rate before treatment and after treatment was observed. Results There were differences in TGCV and gastric emptying rate at different time points in the three groups (P < 0.05). There were significant differences in TGCV and gastric emptying rate among the three groups (P < 0.05). There were differences in the changing trends of TGCV and gastric emptying rate among the three groups (P < 0.05). The gastric emptying rates before and after treatment were significantly different in the EPS group and the PDS group (P < 0.05). Conclusions Contrast-enhanced ultrasonography can be used as an objective tool to evaluate the efficacy of FD patients. The traditional treatment is better for PDS patients than for EPS patients.