Abstract:Objective To investigate the effect of two surgical methods of resection and seton in the treatment of high complex anal fistula. Methods Totally 125 cases of high complex anal fistula patients were divided into two groups according to the order of admission. In the group A, 59 patients underwent modified resection, and 66 patients in the group B underwent modified thread-drawing therapy. The hospitalization time, wound healing time, wound scar size, duration of pain, degree of pain, short-term and long-term curative effect, anal function, anorectal dynamics, postoperative complications and sequelae were observed. Results The length of hospital stay, wound healing time and duration of pain were shorter and the scar size was smaller in the group B than in the group A, the differences were statistically significant (P < 0.05). The long-term recurrence rate was not significantly different between the two groups (P > 0.05). The VAS score of postoperative pain in the group A was higher than that in the group B, and the difference was statistically significant (P < 0.05). There was no significant difference in anal function Wexner score, anal resting pressure or anal maximal contraction pressure between the two group (P > 0.05). Postoperative complications occurred in 1 of the 59 cases in the group A, however, there was no sequelae in either group. Conclusions The improved resection, suture and thread-drawing therapy has the same effect in the treatment of high complex anal fistula, with few complications and sequelae, and the improved resection can shorten the healing time and reduce postoperative pain.