血管性认知功能障碍与常规检查的相关性分析

Study on the correlation between vascular cognitive impairment and routine examinations

摘要:

目的 探讨常规检查与血管性认知功能障碍（VCI）的相关性。方法 选取2015 年1 月—2015 年 12 月在锦州医科大学附属第一医院神经内科就诊的缺血性脑卒中患者239 例，将患者分为正常组、血管性 痴呆组及血管性认知功能障碍非痴呆型组，对患者的一般资料、伴随疾病、实验室检查、颈动脉彩超及神 经心理学结果进行评估和分析。结果 3 组患者年龄和文化程度比较，差异有统计学意义（P <0.05）；3 组 患者慢性阻塞性肺疾病、高脂血症、高血压、低密度脂蛋白、血糖、总胆固醇、白蛋白及谷草转氨酶比较， 差异有统计学意义（P <0.05）；正常组在神经心理学评估MoCA 和MMSE 得分上高于其他两组（P <0.05）。 结论 常规检查与VCI 具有相关性，可用于早期筛查和协助诊断VCI。

Abstract:

Objective To study the correlation between routine examination and vascular cognitive impairment (VCI). Methods From January to December 2015, 239 patients with ischemic stroke admitted to our hospital were collected. Patients were divided into normal group, vascular dementia group and vascular cognitive impairment without dementia group. The general information, comorbidity, laboratory tests, ultrasonography of carotid artery and neuropsychological results of patients were assessed and analyzed. Results ① There were significant differences in age and degree of education among the three groups (P<0.05). ② There were significant differences in chronic obstructive pulmonary disease, hyperlipidemia, hypertension, low density lipoprotein, blood sugar, total cholesterol, albumin and aspartate aminotransferase among the three groups (P<0.05). ③ In the normal group, the MoCA and MMSE scores were higher in the neuropsychological assessment than those in the other two groups (P<0.05). Conclusions Routine examinations are relevant to VCI and can be used to assist in the diagnosis of early screening and VCI.