3种辅助检查诊断涎腺肿瘤符合率的比较研究*

A comparative study on coincidence rate of three assistant examinations in diagnosis of salivary gland tumors*

摘要:

目的 通过研究口腔涎腺肿瘤不同检查的诊断符合率，为临床提供术前快速、简便、有效、低成本 的诊断方法。方法 回顾性分析274例常见涎腺肿瘤B超检查、细针吸取细胞学和术中冷冻切片镜检，并与术后组织病理学检查进行对比。结果 ①B超与石蜡切片对比总的定性诊断符合率为83.2%，其中良性肿瘤的诊断符合率为85.2%，恶性肿瘤符合率为73.3%。②细针吸取细胞学与石蜡切片对比总的定性诊断符合率为87.0%，其中良性肿瘤为88.6%，恶性肿瘤为79.2%；明确诊断总的符合率为63.8%，其中良性肿瘤为64.0%，恶性肿瘤为62.5%。③冷冻切片与石蜡切片对比总的定性诊断符合率为94.9%，其中良性肿瘤为97.4%，恶性肿瘤为83.0%。结论 术中冷冻切片对于涎腺肿瘤的诊断符合率较细针吸取细胞学及B超检查的符合率高，但细针吸取细胞学与B超在术前诊断和治疗计划中有很好的辅助作用。

Abstract:

Objective To investigate the diagnostic accuracy of B-ultrasonography, fine needle aspiration biopsy, and peri-surgical frozen section biopsy in oral salivary glands tumors. Methods Totally 274 cases with salivary gland tumors were involved in this study. B-ultrasonography, fine needle aspiration biopsy and peri-surgical frozen section biopsy were performed in all patients. Diagnostic accuracy of the tools was confirmed with the postoperative histopathological examination. Result The total qualitative diagnostic accuracy of B-ultrasonography was 83.2%, of which the benign tumor and malignant tumor was 85.2% and 73.3%, respectively. The total qualitative diagnostic accuracy of fine needle aspiration biopsy was 87.0%, of which the benign tumor and malignant tumor was 88.6% and 79.2%, respectively. The definite diagnosis rate was 63.8%, of which the benign tumor and malignant tumor was 64.0% and 62.5%, respectively. The total qualitative diagnostic accuracy of peri-surgical frozen section biopsy was 94.9%, of which the benign tumor and malignant tumor was 97.4% and 83.0%, respectively. Conclusions Diagnostic accuracy of peri-surgical frozen section biopsy is satisfactory while the fine needle aspiration biopsy and B-ultrasonography are good pre-surgical diagnostic tools.