Abstract:Objective To evaluate the analgesic effect of quadratus lumborum block and fascia iliaca compartment block in elderly patients with total hip arthroplasty. Methods A total of sixty elderly patients with ASA Ⅱ or Ⅲ received total hip arthroplasty via unilateral approach under single spinal anesthesia. Patients were enrolled and randomly divided into 2 groups (n?=?30): quadratus lumborum block ground (ground A) and fascia iliaca compartment block ground (ground B). Patients in group A ground received posterior puncture approach of quadratus lumborum block (QL3) with 0.25% ropivacaine under the guidance of ultrasound. Patients in group B received fascia iliaca compartment block with 0.25% ropivacaine under the guidance of ultrasound. All the patients received patients-controlled intravenous analgesia. General parameters of the patients, the performance time, resting and the exercise VAS scores at various time points [6 h (T1), 8 h (T2), 12 h (T3), 24 h (T4) after the operation], amount of Sufentanil, complications, and satisfaction score at postoperative 24 h were recorded. Results Patients in group A experienced decreased levels of resting and the exercise VAS scores at the T1, T2, T3, T4 compared with those in ground B (P?0.05). Cumulative amount of sufentanil in group A were significantly less than that of group B (P?0.05). The satisfaction score of ground A were significantly increased than that of ground B (P?0.05). Conclusions Ultrasound-guide quadratus lumborum block is a safe and satisfactory approach for postoperative analgesia in elderly patients with total hip arthroplasty.