Abstract:Objective To evaluate the clinical application of cuffed endotracheal tube in pediatric patients undergoing tonsil radiofrequency ablation surgery. Methods Totally 100 children aging from 3 years old to 8 years old received tonsil radiofrequency ablation in Tianjin Children’s Hospital from December 2017 to January 2018. Clinical performance of cuffed and uncuffed endotracheal tube were recorded. The primary endpoint was the stridor after extubation, and the secondary endpoints included leakage during controlled respiration, tube exchange after intubation, lowest value of SpO2 after extubation, and complications related to intubation. Results No significant difference in gender, age, weight, size of endotracheal tube, and time of duration of intubation were observed between two groups. There was 1 patient with air leakage and 1 patient needed to switch tube size in cuffed group. There were 11 patients with air leakage and 8 patients needed to switch tube size in uncuffed group (P?0.05). No significant difference in stridor while extubating or the lowest value of SpO2 were observed between two groups (P?> 0.05). Six patients in uncuffed group had bloody secretion after extubation while no complications occurred in cuffed group (P?0.05). Conclusions The cuffed endotracheal tube is safe for children under 8 years old undergoing tonsil radiofrequency ablation surgery.