宫颈癌根治术中用血风险因素的评估

Evolution of blood risk factors in radical resection of cervical cancer

摘要:

目的 通过对宫颈癌根治术患者的用血情况及相关因素进行分析，探讨宫颈癌根治术中输血的风险因素，为术前评估术中用血风险提供参考。方法 选取2013年7月1日—2016年11月30日中国医科大学附属盛京医院行宫颈癌根治术且进行术前交叉配型的患者427例，排除记录不全47例，将剩余380例患者按术中是否输注滤白红细胞分为输血组（53例）和未输血组（327例），比较两组患者基本信息、术前实验室检查、手术相关因素、肿瘤相关因素及术前合并疾病等差异，并进行二元Logistic回归分析。结果 各类因素均进行组间比较，其中是否合并化疗、术前血红蛋白、术前血小板、手术方式及肿瘤分期在两组间的差异有统计学意义（P?<0.05）。多因素分析结果显示，是否化疗、术前血红蛋白和血小板水平是术中输血的危险因素（P?<0.05）。结论 影响宫颈癌根治术术中用血的相关危险因素主要有术前是否化疗、术前血红蛋白及血小板水平。

Abstract:

Objective To investigate the risk factors of blood transfusion in radical resection of cervical cancer by analyzing the blood use and related factors in patients undergoing radical resection of cervical cancer, and to provide a reference for preoperative evaluation of blood risk during surgery. Methods A total of 427 patients who underwent radical resection of cervical cancer at Shengjing Hospital of China Medical University from July 1, 2013 to November 30, 2016 were selected (exclusion of incomplete records of 47 cases). Patients were divided into 2 groups according to whether they have received preoperative surgical transfusion or not. Basic information, preoperative laboratory examination, surgical related factors, tumor related factors and preoperative complications were compared and analyzed. Results All the factors were compared between the groups. The differences of whether there were chemotherapy, preoperative hemoglobin, preoperative platelets, surgical methods and tumor stage were statistically significant (P?