声触诊组织量化在精索静脉曲张不育中的应用

Application of acoustic palpation tissue quantification in infertility due to varicocele

摘要:

目的 分析声触诊组织量化在精索静脉曲张（VC）不育中的应用价值。方法 选取2017 年 7 月—2018 年1 月于安徽医科大学附属省立医院不孕不育男科门诊就诊，并经超声诊断为左侧VC 的90 例患 者作为VC 组，选取同期该院49 例健康体检者作为对照组，对两组实施声触诊组织量化检测，并根据VC 超 声诊断标准分为亚临床型精索静脉曲张（SVC）和临床型静脉曲张（VC Ⅰ、VC Ⅱ及VC Ⅲ），比较精液常 规结果的差异。结果 VC Ⅰ组、VC Ⅱ组及VC Ⅲ组左右侧睾丸组织剪切波速度值均低于对照组（P <0.05）； SVC 组左右侧睾丸组织剪切波速度值均高于VC Ⅱ组、VC Ⅲ组（P <0.05）；VC Ⅰ组左右侧睾丸组织剪切波 速度值均高于VC Ⅱ组、VC Ⅲ组（P <0.05）；VC Ⅰ、VC Ⅱ及VC Ⅲ组精子密度、精子活率均低于对照组 （P <0.05）；SVC 组精子密度、精子活率均高于VC Ⅰ组、VC Ⅱ组及VC Ⅲ组（P<0.05）；VC Ⅰ组精子密度、 精子活率高于VC Ⅱ组、VC Ⅲ组（P <0.05），VC Ⅱ组精子密度、精子活率高于VC Ⅲ级组（P <0.05）。VC 组睾丸组织剪切波速度值与精子密度、精子活率呈正相关（P <0.05）。结论 声触诊组织量化技术测量睾丸 组织剪切波速度值可作为预测VC 患者精液质量的重要参考指标。

Abstract:

Objective To analyze the application value of virtual touch tissue quantification (VTQ) in varicocele (VC) infertility. Methods A total of 90 patients with infertility of VC were set to VC group, and 49 cases of normal physical examination were set to a control during this period. According to the VC type ultrasonic diagnostic criteria, the two groups were divided into subclinical varicocele (Subclinical varicocele, SVC) and clinical varicocele (VC Ⅰ, VC Ⅱ, VC Ⅲ). The semen routine results were compared. Results The shear wave velocities of left and right testicular tissues in VC Ⅰ group, VC II group and VC III group were lower than those in control group (P < 0.05); the shear wave velocities of left and right testicular tissues in SVC group were higher than those in VC II group and VC III group (P < 0.05); the shear wave velocities of left and right testicular tissues in VC Ⅰ group were higher than those in VC II group and VC III group (P < 0.05); sperm density and sperm viability in VC Ⅰ, VC II and VC III groups were lower than those in control group (P < 0.05). Sperm density and sperm viability in SVC group were higher than those in VC Ⅰ group, VC II group and VC III group (P < 0.05), sperm density and sperm viability in VC Ⅰ group were higher than those in VC II group and VC III group (P < 0.05), and sperm density and sperm viability in VC II group were higher than those in VC III group (P < 0.05). The shear wave velocity of testicular tissue in VC group was positively correlated with sperm density and sperm viability (P < 0.05). Conclusions VTQ technique can be used as an important reference index to predict the semen quality of VC patients.