中性粒细胞/ 淋巴细胞比值对大肠埃希菌 血流感染的诊断价值

Value of neutrophil/lymphocyte ratio in bloodstream infection of Escherichia coli

摘要:

目的 研究白细胞（WBC）、中性粒细胞绝对值（NEU）、淋巴细胞绝对值（LYM）、中性粒 细胞/ 淋巴细胞比值（NLR）、超敏C 反应蛋白（hs-CRP）及降钙素原（PCT）在大肠埃希菌血流感染中 的意义。方法 以50 例明确为大肠埃希菌血流感染的患者作为研究对象（实验组），选取50 例血培养阴性 患者作为对照组。检测全血细胞计数、hs-CRP 及PCT，绘制ROC 曲线预测诊断价值。结果 实验组患 者WBC、NEU、NLR、hs-CRP 及PCT 高于对照组（P <0.05）。NLR 诊断大肠埃希菌血流感染的曲线下 面积为0.728。结论 NLR 用于诊断大肠埃希菌血流感染的综合价值优于WBC、NEU、LYM、hs-CRP 及 PCT，NLR 联合PCT 可作为早期诊断指标。

Abstract:

Objective To study the meaning of white blood cell(WBC), neutrophil absolute value (NEU), lymphocyte absolute value (LYM), neutrophil/lymphocyte ratio (NLR), high-sensitivity C-reactive protein (hs- CRP) and procalcitonin (PCT) in bloodstream infection caused by Escherichia coli. Methods Totally 50 patients of bloodstream infection caused by Escherichia coli were enrolled and 50 healthy people were collected as the control group. Blood routine, hs-CRP and PCT were measured and compared. The diagnostic value was determined by ROC curve. Results The WBC, NEU, NLR, hs-CRP and PCT of the infection group were higher than that of the control group, and the LYM was lower. There were statistically significant differences in WBC, NEU, NLR and PCT between the two groups (P < 0.05). The area under the curve of NLR in diagnosing bloodstream infection caused by Escherichia coli is 0.728. Conclusions The value of NLR in diagnosing bloodstream infection caused by Escherichia coli is better than that of WBC, NEU, LYM, hs-CRP and PCT. NLR can be combined with PCT as an early diagnostic indicator.