家属参与式教育对2型糖尿病患者代谢指标影响的Meta分析*

Effect of family participatory health education on metabolism in patients with type 2 diabetes: a Meta-analysis*

摘要:

目的 评价家属参与式教育对2型糖尿病患者代谢指标产生的效应。方法 通过计算机检索多个中英文数据库中的相关文献，然后对符合纳入、排除标准的随机对照研究进行评价，最后采用Stata 14.0和RevMan5.3 两种软件进行分析。结果 纳入的随机对照试验共有11篇。相对于对照组的2型糖尿病患者，家属参与式教育组在降低糖化血红蛋白方面，3个月内[WMD=-0.50（95% CI：-0.61，-0.39），P?=0.000]、3～6个月[WMD= -0.57（95% CI：-0.69，-0.45），P?=0.000]，以及6个月以后[WMD=-0.49（95% CI：-0.76，0.21），P?=0.000]，两组间差异有统计学意义；在降低空腹血糖水平上差异也有统计学意义[WMD=-17.44，（95% CI：-23.01，-11.87），P?=0.000]；然而在改善体重指数、总胆固醇、甘油三酯、高密度脂蛋白和低密度脂蛋白水平等指标，差异无统计学意义（P?>0.05）。结论 针对2型糖尿病患者，家属参与式教育有利于长期改善患者的血糖管理情况，而对体重指数和脂质代谢指标的作用效果尚不能得出确定答案，有待临床开展设计合理的、样本量大的随机对照研究进行验证。

Abstract:

Objective To evaluate the effect of family participatory education on metabolicsm in patients with type 2 diabetes. Methods Randomized controlled trials that assess the effectiveness of family participatory education in patients with type 2 diabetes were systematically reviewed using multiple electronic databases. Results A total of 11 randomized controlled trials were included. The meta-analysis showed that, compared with control group, family participatory education lowered glycated hemoglobin levels within 3 months [WMD?=?-0.50, (95%CI: -0.61, -0.39), P??0.05) between control group and family participatory education group. Conclusions family participatory education helps control blood glucose but exerts no obvious effect on body mass index and lipid metabolism.