急性胰腺炎患者饥饿感时经口进食的临床研究

Correlation of hunger and oral refeeding in the treatment of acute pancreatitis

摘要:

目的 探讨中度急性胰腺炎（AP）患者饥饿感与经口进食的可行性和安全性。方法 选取2015 年 6 月—2018 年6 月在河南大学第一附属医院消化内一科住院的120 例中度AP 患者，随机分为早期经口进食 组（早期组）和常规经口进食组（常规组），每组60 例。早期组患者自感饥饿时即给予经口进食，常规组在 患者各项指标正常且无腹痛时准予进食，对两组临床指标及并发症发生情况进行比较。结果 早期组经口 进食前血清淀粉酶、血清脂肪酶、白细胞计数及血糖高于常规组（P <0.05）。早期组出院前血糖高于常规组 （P <0.05）。早期组总住院时间和腹痛恢复时间均低于常规组（P <0.05）。结论 以患者的主观饥饿感做为中 度AP 患者恢复经口进食的标准是安全、有效和可行的。

Abstract:

Objective To investigate the feasibility and safety of early oral feeding and self-feeled hunger in patients with moderate acute pancreatitis. Methods A total of 120 patients with moderate acute pancreatitis were randomly divided into early oral refeeding (EORF) group and conventional oral refeeding (CORF) group, 60 cases in each group. Patients in EORF group with were given food through the mouth when they felt hungry, and patients in CORF group were allowed to eat when laboratory parameters were normal and they were without abdominal pain. Clinical indexes and complications between the two groups were observed and compared. Results The serum amylase, lipase, white blood cell count and blood sugar of the EORF group before oral feeding were higher than those of the CORF group (P < 0.05). The blood sugar of the EORF group was higher than that of the CORF group before discharge (P < 0.05). The total hospitalization time and recovery time of abdominal pain in EORF group were lower than those in CORF group (P < 0.05). Conclusions It is safe and feasible to use the subjective hunger of patients as the criterion to restore oral feeding in patients with moderate acute pancreatitis.