FN与PTEN在原发性肝癌患者血清中的表达及联合诊断与预后评估的价值

Clinical significance of serum FN and PTEN in primary liver cancer patients

摘要:

Abstract:

Objective To analyze expression and clinical significance of serum FN and PTEN in primary liver cancer patients. Methods A total of 256 primary liver cancer patients as well as 50 healthy subjects who were admitted into our hospital from January 2013 to October 2015 were involved in this study. Cancerous tissue and para-cancer tissue were collected. Expression of FN and PTEN were tested by RT-PCR and western-blot. ROC curve was used to evaluate the diagnostic value of FN and PTEN. Results Expression of FN was increased while that of PTEN was decreased in cancer liver tissue significantly when compared with paracancerous tissue or normal liver (P?