三丙烯微球联合碘油在脾动脉部分栓塞术中的应用*

Application of microsphere embolism plus lipiodol in partial splenic artery embolization*

摘要:

目的 探讨三丙烯微球联合碘油在脾动脉部分栓塞术中（PSE）的应用价值。方法 按前瞻性随机对照研究原则将180例患者分为三丙烯微球栓塞组（1组）、三丙烯微球联合碘油栓塞组（2组）及明胶海绵栓塞组（3组）。给予相应的PSE治疗，统计各组患者疗效（3及6个月白细胞、血红蛋白及血小板检测值和达到正常值例数）及并发症（发热、腹膜炎及持续时间、腹痛的程度及持续时间）情况；统计各组患者6个 月栓塞血管再通数。结果 1组与2组疗效及6个月栓塞血管再通例数比较，差异无统计学意义（P?>0.05），1组与2组均高于3组（P?<0.05）；2组术后腹膜炎天数及腹痛持续时间均短于1组和3组（P?<0.05）。结论 三丙烯微球联合碘油栓塞在PSE中应用是安全有效的，能减轻并发症的强度。

Abstract:

Objective To observe the application of microsphere embolism plus lipiodol in partial splenic artery embolization. Methods A prospective controlled study was applied, which contained 180 patients and were randomly divided into the microsphere embolism embolization group (group 1), microsphere embolism united lipiodol group (group 2) and gelatin sponge embolization group (group 3). Effectiveness index including WBC, HGB, PLT, the number of cases reaching normal value at 3 and 6 months after treatment, and complications including fever, peritonitis and abdomen pain, and the number of vascular reperfusions at 6 months after treatment were recorded. Results Patients in group 1 and group 2 exerted increase in effectiveness and the number of vascular reperfusion 6 months after treatment when compared with group 3 while no statistically significant differences were found between group 1 and group 2. Patients in group 2 had shorter duration of peritonitis, fever and abdominal pain when compared with those in group 3. Conclusions Microsphere embolism plus lipiodol is safe and effective in splenic artery embolism without increasing complications.