Abstract:Objective To assess the short-term clinical outcome of opening wedge valgus-producing osteotomy compared with Oxford Ⅲ unicompartmental knee replacement in medial unicompartmental osteoarthritis (OA) of the knee that is not only suitable for HTO but also for UKA. Methods We designed retrospective study 40 patients with medial unicompartmental osteoarthritis (OA) of the knee in our department between January 2016 and January 2017. Two groups of patients underwent arthroscopy combined with HTO in 18 cases (HTO group) and arthroscopy combined with UKA in 22 cases (UKA group). Closing wedge osteotomy was used in HTO group, and Biomet Oxford Ⅲ unicompartmental knee prosthesis in UKA group. All patients were followed up (18.88±5.18) months on average. The operative time, intraoperative blood loss, bed rest time, visua analog scale (VAS) score, The Knee Injury and Osteoarthritis Outcome Scores (KOOS), International Knee Documentation Committee (IKDC) Score, Lysholm knee score, femorotibialangle (FTA) and knee range of motion (ROM) were compared between two groups. Results KOOS, IKDC and Lysholm knee joint scores were higher in the last follow-up of the two groups than before (P < 0.05), VAS score was lower than before (P < 0.05), and tibiofemoral angle was lower in the last follow-up of the two groups than before (P < 0.05). Conclusions Both HTO and UKA are effective methods for the medial unicompartmental osteoarthritis patients that are not only suitable for HTO but also for UKA. The short-term effectiveness are satisfactory and with no significant difference, but the long-term effectiveness need further follow-up observation.