哈萨克族食管癌骨转移瘤患者核素骨显像的特征分析

Characteristics of radionuclide bone scintigraphy in bone metastases of Kazakh patients with esophageal cancer

摘要:

目的 探讨新疆哈萨克族食管癌骨转移瘤患者核素骨显像的特征及临床价值。方法 选取2013年1月— 2017年12月在新疆维吾尔自治区人民医院行核素全身骨扫描的哈萨克族食管癌患者73例，归纳哈萨克族食管癌患者骨转移显像特点，另选取115例行核素骨显像的汉族食管癌患者进行对照，对比两组患者间的骨转移瘤特征及病理类型与骨转移关系的相关数据。结果 24例哈萨克族骨转移瘤患者中肋骨、脊柱骨、骨盆骨、四肢骨及胸锁骨的转移率分别为87.50%（21/24）、29.17%（7/24）、16.67%（4/24）、29.17%（7/24）和8.33%（2/24），无一例颅骨转移。48例汉族食管癌骨转移瘤患者中，肋骨、脊柱骨、骨盆骨、四肢骨、胸锁骨及颅骨的转移率分别为39.58%（19/48）、56.25%（27/48）、25.00%（12/48）、33.33%（16/48）、16.67%（8/48）和4.17%（2/48）。在肋骨及脊柱骨的转移发生率中，两组数据差异有统计学意义（P?<0.05），哈萨克族食管癌患者的肋骨转移率要高于汉族食管癌患者，汉族食管癌患者的脊柱骨转移率要高于哈萨克族食管癌患者。两组骨痛情况比较，差异无统计学意义（P?>0.05）。两组食管癌患者鳞状细胞癌、腺癌及未分化癌的骨转移发生率比较，差异无统计学意义（P?>0.05）。结论 核素骨显像对哈萨克族食管癌患者具有临床意义，可在临床工作中广泛应用。

Abstract:

Objective To investigate the characteristics and clinical value of radionuclide bone imaging in patients with bone metastases of esophageal cancer from Kazakh in Xinjiang. Methods Seventy-three patients with esophageal cancer from Kazakh who underwent radionuclide whole body bone scan in the Department of Nuclear Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region from January 2013 to December 2017 were selected to summarize the characteristics of bone metastasis. 115 patients with esophageal cancer from Han who underwent radionuclide bone imaging were selected for comparison. The data of bone metastasis and the relationship between pathological type and bone metastasis were compared between the two groups. Results The transfer rates of rib, spine, pelvic bone, limb bone and sternoclavicular in 24 Kazakh patients with bone metastases were 87.50% (21/24), 29.17% (7/24), and 16.67% (4/24), 29.17% (7/24) and 8.33% (2/24) respectively, without any skull metastases. In 48 patients with Han patients with esophageal cancer, the transfer rates of ribs, spine bone, pelvic bone, limb bone, sternum clavicle and skull were 39.58% (19/48), 56.25% (27/48), 25.00% (12/48), 33.33% (16/48), 16.67% (8/48) and 4.17% (2/48) respectively. In the incidence of rib and spine bone metastasis, the difference between the two groups was statistically significant (P??0.05). There was no significant difference in the incidence of bone metastases between squamous cell carcinoma, adenocarcinoma and undifferentiated carcinoma in patients with esophageal cancer (P?>?0.05). Conclusion Radionuclide bone imaging has important clinical significance for Kazakh patients with esophageal cancer and is worth of promotion.