Abstract:Objective To investigate the situation of hospital infection, and provide ecidence for prevention and control of hospital infection. Method According to the requirements of the National Hospital Infection Surveillance Network, the current prevalence rate in each year from 2013 to 2017 was investigated and the data were statistically analyzed. Results The prevalence rate of hospital infections in 2013 to 2017 were 3.96%, 3.24%, 2.89%, 3.83%, and 4.53%, respectively, and the difference was not statistically significant (P?>?0.05). The department with the highest prevalence rate in 5 years is the ICU, and the highest infection site is the lower respiratory tract. The average use rate of antibacterial drugs was 22.13%, the therapeutic drug use rate increased, and the preventive drug use rate decreased, and the difference was statistically significant (P?0.05). The number of Gram-negative bacilli was the highest among the isolated pathogens, and the multi-drug resistance rate of Acinetobacter baumannii was the highest. Analysis showed that age, ventilator, arteriovenous catheter, catheter, and surgery were risk factors for nosocomial infection. Conclusions The prevalence rate survey is helpful to understand the actual situation of hospital infections. The results suggest that the management of key departments and key populations should be strengthened, the lower respiratory tract infections should be paid attention to, the rational use of antibiotics should be regulated, and effective preventive measures should be taken to reduce the incidence of nosocomial infections.