维生素D 缺乏与心血管疾病危险因素 关系的研究进展

Research progress on relationship between vitamin D deficiency and cardiovascular risk factors

摘要:

目前心血管疾病患病率及病死率仍处于上升阶段，心血管疾病病死率居于首位，高于肿瘤和其 他疾病，在居民病死率构成中占40% 以上。该文主要讨论维生素D 缺乏与心血管疾病危险因素（血脂异常、 肥胖、高血压及糖尿病）的关系，以及其对冠状动脉粥样硬化性心脏病、心力衰竭及心房颤动等常见心血管 系统疾病的影响。目前一些观察性研究和部分动物实验提示维生素D 可能对心血管系统起保护作用，但是现 有的临床实验证据不支持补充维生素D 使心血管受益或危害。

Abstract:

The prevalence and mortality of cardiovascular disease in China is still on the rise, and the mortality rate of cardiovascular diseases ranks first, higher than tumors and other diseases, accounting for more than 40% of the deaths of residents. This article mainly discusses the relationship between vitamin D deficiency and cardiovascular risk factors (dyslipidemia, obesity, hypertension, diabetes mellitus), and its effects on common cardiovascular diseases such as coronary heart disease, heart failure, atrial fibrillation. At present, some observational studies and some animal experiments show that vitamin D may protect the cardiovascular system, but the existing clinical experimental evidence does not support the vitamin D to benefit or harm the cardiovascular.