Abstract:SARS-CoV-2 was discovered in Wuhan, China in December 2019. Due to the strong infectivity of this novel coronavirus, the epidemic situation took Hubei Province as the center and quickly spread to the whole country with the help of the huge population flow during the Spring Festival. It is of great significance to recognize the change of epidemic disease and understand the research and development progress of clinically targeted drugs for controlling COVID-19. This article reviews and evaluates the characteristics of SARS-CoV-2, the epidemiological manifestations of COVID-19, the research and application of therapeutic drugs, etc.