Abstract:Facing severe situation caused by novel coronavirus pneumonia, public hospital discipline inspection department took the prevention and control of the epidemic as priority in order to promoting the comprehensive and strict development of the party. This article uses Xiangya Hospital of Central South University as an example to analyze the inspection mechanism, inspection form and inspection measures of public hospital discipline inspection department during the epidemic prevention and control period. On the basis of summing up relevant experience, this article provides the suggestions of public hospital discipline inspection department in responding to public health emergencies, which has a certain reference significance for enhancing medical institutions’ capability in supervising and guiding epidemic prevention and control.