Abstract:Objective To analyze the influencing factors of interpartum fever in pregnant women with epidural labor analgesia. Methods Among 150 parturients who received epidural analgesia, 44 had fever during delivery (fever group) and 106 had normal temperature during delivery (normal group). The general demographic characteristics and epidural analgesia administration were compared between the two groups, and the influencing factors of interpartum fever were identified by logistic multivariate regression analysis. Results In the fever group, the proportion of primipara, prenatal depression, prenatal anxiety and BMI were higher than those in the normal group (P?0.05); The time from rupture of membranes to the end of delivery, labor process and labor analgesia were longer (P?0.05); the frequency of vaginal examination was more (P?0.05); the incidence of amniotic fluid pollution and the use of oxytocin were higher (P?0.05); the percentage of discontinuous epidural analgesia was lower (P?0.05). Multivariate analysis showed that the time from rupture of fetal membranes to the end of delivery [OlR?=?1.014, (95% CI: 0.924, 1.556)], labor process [OlR?=?1.114, (95% CI: 0.984, 1.526)], number of vaginal examinations (OlR? =?1.547, (95% CI: 1.140, 3.246)], labor analgesia time [OlR?=?1.122, (95% CI: 1.036, 1.769)], oxytocin use [OlR?= 2.160, (95% CI: 1.774, 2965)], BMI [OlR?=?2.324, (95% CI: 1.057, 2.965)] and epidural analgesia administration [OlR?=?1.322, 95% CI: 1.247, 3.668)] were all risk factors for intrapartum fever during epidural analgesia. Conclusion There are many factors influencing the occurrence of intrapartum fever (such as BMI, duration of labor, number of vaginal examinations, duration of labor analgesia, administration of epidural analgesia, etc.). In order to reduce the risk of intrapartum fever, we should intervene or adjust the administration of epidural analgesia in time according to the aforementioned factors.