中药对新生儿黄疸血清胆红素水平的影响*

Effect of traditional Chinese medicine on the level of serum bilirubin in neonatal jaundice*

摘要:

新生儿黄疸是新生儿出生后最常出现的临床症状之一，临床上常用血清胆红素水平的高低来评估患儿的黄疸程度，在出生后24?d出现黄疸的婴儿，尤其是由于溶血引起的黄疸，有发展为急性和慢性胆红素脑病的风险。现代研究表明，中医治疗新生儿黄疸具有较好的临床疗效，并且中药可通过调节胆红素代谢、调控胆汁酸合成与转运、抑制免疫与炎症反应、影响肝脏胶原形成等多个途径发挥治疗新生儿黄疸的作用。

Abstract:

Neonatal jaundice is one of the most common clinical symptoms of newborns. The level of serum bilirubin is commonly used to evaluate the degree of jaundice in children. Infants with jaundice, especially that caused by hemolysis within 24 days after birth, are at risk of developing acute and chronic bilirubin encephalopathy. Modern research shows that traditional Chinese medicine has good clinical efficacy in the treatment of neonatal jaundice, and traditional Chinese medicine can play a role in the treatment of neonatal jaundice by regulating bilirubin metabolism and bile acid synthesis and transport, inhibiting immune and inflammatory reactions, affecting liver collagen formation and other mechanisms.