Abstract:To compare the morbidity of hyperkalemia and hypokalemia between patients under-going peritoneal dialysis (PD) and hemodialysis (HD), and analyze the causes. Methods All patients were enrolled from the Department of Nephrology, Suizhou Hospital and divided into PD group (30 cases) and HD group (32 cases). The follow-up duration was 6 months. Blood routine, liver and kidney functions, and electrolytes were measured every month, the mean serum kalium level was calculated and the frequency of hyperkalemia and hypokalemia were recorded. Results The mean level of serum kalium in the PD group was significantly lower than that in the HD group (p < 0.05). The frequency of hyperkalemia in the PD group (3.3%) was lower than that in the HD group (34.4%), the diferrence was significantly. The incidence of hypokalemia in the HD group (0.00%) was significantly lower than that in the PD group (10.34%). Conclusions Compared with HD, PD can better prevent hyperkalemia, but the occurrence rate of hypokalemia is higher. No matter what kind of dialysis method is selected, it is important to prevent abnormal serum kalium.