脑电双频谱指数对急性严重脑损伤患者的预后分析

Value of bispectral index in prediction of prognosis of patients with acute severe brain injury

摘要:

目的 探究脑电双频谱指数（BIS）用于预测急性严重脑损伤患者预后的价值。方法 回顾性分析2013 年6 月-2015 年6 月该院收治的46 例急性严重脑损伤患者的临床资料，将存活的28 例患者作为生存组，死亡的18 例患者作为死亡组，所有研究对象均于入院24 h 行BIS 监测，同时对两组患者反应水平量表（RLS85）和急性生理学与慢性健康状况评分系统Ⅱ（APACHE Ⅱ）及基本资料进行分析，比较两组患者之间的差异，分析BIS 分别和RLS 85 及APACHE Ⅱ评分之间的相关性，并对影响急性严重脑损伤患者预后的因素进行Logistic 回归分析。结果 生存组APACHE Ⅱ评分与RLS85 评分均低于死亡组（P <0.05），生存组BIS 值高于死亡组（P <0.05）；BIS 值与APACHE Ⅱ评分与RLS85 评分呈负相关（P <0.05）；多因素Logistic回归分析显示，BIS 值是影响患者预后的独立危险因素。结论 BIS 可用于预测急性严重脑损伤患者预后，同时对临床上病情评估和治疗方案选择也具有重要作用。

Abstract:

Objective To explore the value of bispectral index (BIS) in predicting the prognosis of patients with acute severe brain injury. Methods The clinical data of 46 patients with acute severe brain injury in our hospital from June 2013 to June 2015 were retrospectively analyzed, the 28 cases survived were as the survival group, and the 18 cases died were as the death group. All of the research subjects were given BIS monitoring 24 h after admission.Their Reaction Level Scale (RLS85) score and Acute Physiology and Chronic Health Evaluation Scoring System II (APACHE II) score were analyzed at the same time. The differences between the two groups were compared, and the correlations of BIS with RLS85 score and APACHE II score were analyzed. Results The scores of APACHE II and RLS85 in the survival group were statistically lower than those in the death group (P < 0.05), while the value of BIS in the survival group was significantly higher than that in the death group (P < 0.05). The BIS value was negatively correlated with scores of APACHE II and RLS85 (P < 0.05). Multivariate logistic regression analysis showed that BIS was an independent risk factor affecting the prognosis of patients. Conclusions BIS can be used to predict the prognosis of patients with acute severe brain injury, at the same time, it has an important role in clinical evaluation and treatment options.