糖尿病患者代谢综合征患病状况及影响因素分析

Prevalence of metabolic syndrome in patients with diabetes mellitus

摘要:

了解糖尿病患者代谢综合征（MS）的患病状况。方法选取2012 年1 月-2015 年2 月桐乡市第二人民医院门诊和病房收治的283 例初诊糖尿病患者为研究对象，参考2010 年中国高血压防治指南修订版中MS 的诊断标准将患者分为MS 组和非MS 组，比较不同性别、年龄组患者的MS 及其他组分的患病情况，采用多因素Logistic 回归分析患者发生MS 的影响因素。结果190 例（67.1%）糖尿病患者患有MS，其中女性MS 的患病率为75.6%，高于男性患者的63.2%（ p<0.05）。青年、中年、老年患者MS 的患病率分别为51.4%、 67.0%和77.1%，其中女性患者中各年龄组的患病率分别为41.7%、75.9%和95.0%，3 组比较差异均有统计学意义（p <0.05）。男性和女性患者中年龄越大，血压升高的发生率越高（ p<0.05）。文化程度和吸烟是青年患者发生MS 的独立影响因素（ p<0.05）性别是中年患者发生MS 的独立影响因素（ p<0.05），性别和生活方式是老年患者发生MS 的独立影响因素（ p<0.05）。结论超过2/3 的糖尿病患者患有MS，女性糖尿病患者的MS 患病率高于男性，MS 和血压升高的患病率随年龄增长均呈升高趋势，吸烟可能增加青年患者MS 患病风险，而体育锻炼可降低老年患者的MS 患病风险。

Abstract:

To analyze the prevalence of metabolic syndrome (MS) among patients with diabetes mellitus. Methods Totally 283 patients with diabetes mellitus in our hospital between January 2012 and February 2015 were enrolled in the study and divided into MS group and control group according to defined diagnostic criteria on MS from the 2010 hypertension guidelines. Prevalence of MS in the patients with different gender or age were compared. Multivariate logistic regression analysis was performed to investigate the related factors of MS. Results Of the 283 patients, 190 cases (67.1%) had MS, and the prevalence of MS in the female patients was 75.6%, which was significantly higher than that (63.2%) of the male patients (p < 0.05). The morbidity of MS in the young, middleaged and elderly patients was 51.4%, 67.0% and 77.1% respectively; and the morbidity of MS in the corresponding age group of the female patients was 41.7%, 75.9% and 95.0% respectively, there were significant differences among all age groups ( p< 0.05). The older the male and female patients, the higher the incidence of elevated BP (p <0.05). Educational level and smoking were the independent factors affecting the prevalence of MS in the young patients with diabetes mellitus ( p< 0.05); gender was the independent factor in the middle-aged patients ( p< 0.05);and gender and lifestyle were the independent factors in the elderly patients ( p< 0.05). Conclusions More than twothirds of patients with diabetes suffer from MS. The incidence of MS in female patients is higher than that in male patients. And the incidences of MS and elevated BP tend to increase with age. Smoking could significantly increase the risk of MS in young patients with diabetes while physical exercise could reduce the risk in elderly patients.