Abstract: Objective To study the impact of intra-urethral catheter on uroflow rate in pressure-flow study. Methods Fifty-four men with benign prostate hyperplasia (BPH) underwent free uroflometry and pressureflow analysis respectively. With an F8 urethral catheter, the standard pressure-flow variables such as the maximum flow and catheter’s uroflow rate were measured and analyzed with paired t test. Results The maximum free uroflow rate and the mean free uroflow rate were significantly different before and after catheterization (P < 0.05). The maximum voided volume in free uroflometry and in pressure-flow study was not statistically different (P > 0.05). There were significant differences in the maximum uroflow rate and the maximum catheter’s uroflow rate among the patients with bladder outlet obstruction of grade II-IV (P < 0.05), but there were no significant differences among the patients with bladder outlet obstruction of grade 0, I, V and VI (P > 0.05). Conclusions F8 urethral catheter appears to have significant impact on uroflow rate.