Abstract:Objective To investigate the application value of ultra-slim electronic transnasal gastroscopy and preoperative communication in the gastroscopic review of patients with early gastric cancer. Methods A total of 400 patients diagnosed with early gastric cancer by gastroscopy and pathologic verification were randomly divided into two groups within three months' review from January 2015 to December 2015, 200 of them were included into the control group (general gastroscope for oral insertion, group I) and the remaining were included in the experimental group (ultra-slim gastroscope for nasal insertion, group Ⅱ). Some of the patients were selected randomly from the groups to receive preoperative communication and notification. Heart rate, blood pressure, vomiting response, body coordination and images were recorded intraoperatively, and acceptance of gastroscopy was measured by questionnaires. Results The patients with early gastric cancer who accepted the ultra-slim gastroscope for nasal insertion (group Ⅱ) performed better range of heart rate and blood pressure than the patients who accepted general gastroscope for oral insertion (group I) (P < 0.05). The patients in group Ⅱhad less vomiting response than those in the group I (X2 = 163.262, P= 0.001). All the patients had preoperative interpretation of slight nausea and vomiting reactions (group I: X2 = 142.431,P =0.042; group Ⅱ: X2 = 152.713,P = 0.034). The patients in the group Ⅱhad better body coordination than those in the group I (X2 = 178.191, P= 0.001). All the patients had preoperative interpretation of good body coordination. (group I: X2 = 151.213,P = 0.032; group Ⅱ: X2 = 158.214,P = 0.024). The patients in the group Ⅱperformed higher acceptance level than those in the group I (X2 =163.262,P = 0.001). All the patients had preoperative interpretation of good acceptance level (group I: X2 = 142.233,P = 0.045; group Ⅱ: X2 = 148.232,P= 0.033). There was no obvious difference in imaging between the groups. Conclusions The patients with early gastric cancer who accepted the ultr-slim gastroscopy for nasal insertion and preoperative communication perform better range of heart rate and blood pressure, less vomiting response, better body coordination and higher acceptance level than the patients who accepted general gastroscopy for oral insertion, which can avoid the occurrence of various adverse reactions.