Abstract:Objective To investigate the prevalence and relevant characteristics of mental disorders among the inpatients in a general hospital, and to describe the recognition of the doctors in non-psychiatric departments of a general hospital and the effect of psychological interventions. Methods This was a hospital-based crosssectional study. A stage of investigation was used. Data collection was conducted among the 597 intpatients from non-psychiatric departments from June to August in 2014 using the Mini International Neuropsychiatry Interview (MINI). Univariate and multivariate analyses were performed using SPSS 22.0. Results The occurrence of mental disorders was 17.6%, including depressive disorder (9.4%), generalized anxiety disorder (3.7%), dysthymia (1.7%),suicidality (1.2%), hypomanic episode (1.2%), panic disorder (0.3%), agoraphobia (0.5%), socialphobia (0.2%),obsessive-compulsive disorder (1.0%), posttraumatic stress disorder (2.0%), alcohol abuse and dependence (2.0%), non-alcohol psychoactive substance use disorder (0.5%), psychotic disorder (0.7%), anorexia nervosa (0.7%), bulimia nervosa (0.2%), and antisocial personality disorder (0.0%). The high prevalence was in four departments including Department of Gastroenterology (44.9%), Rehabilitation Department (25.0%), Geriatric Ward (24.1%) and Department of Neurology (19.0%). The discrimination ratio was 51.4%, the four departments with high discrimination ratio included Department of Neurology (87.5%), Department of Neurosurgery (71.4%), Department of Respiratory Medicine (60.0%) and Geriatric Ward (53.8%). The logistic regression results showed the departments, living styles, history of mental illness and treatment will were the independent risk factors. Conclusions It is noticeable that low incidence and high recognization rate of mental disorders have been found in the inpatients of a general hospital. The inpatients of internal medicine in a general hospital, who live along, have a history of mental disorders, or discriminate the psychopath, are prone to get sick with mental disorders. PTSD should be excluded for the inpatients with traumatic injury.