Abstract:To learn the quality of life and social support status in empty-nest elderly patients with chronic pain, and their relationship. Methods From February to December of 2015, a questionnaire survey was conducted by the application of convenience sampling method, in which general information questionnaire, Quality of Life Scale, Social Support Rating Scale and Short-form McGill Pain Questionnaire were applied to empty-nest elderly patients with chronic pain in Linghe District, Guta District and Taihe District of Jinzhou City, Liaoning Province. Results The scores of quality of life including physiological function, general health, vitality and social function scores in the married elderly patients with chronic pain were significantly higher than those in the elderly living alone (p < 0.05). The total score of social support, objective support score and subjective support score in the married elderly patients with chronic pain were significantly higher than those in the elderly patients living alone(p < 0.05). There was a positive correlation between the quality of life and their social support in the elderly patients with chronic pain. Conclusions Compared to the married empty-nest elderly patients with chronic pain, the quality of life and social support level are relatively low in the empty-nest elderly patients with chronic pain who live alone. The living-alone elderly patients with chronic pain are the most vulnerable group in community elderly patients with chronic pain, they should be given more attention in community care. The quality of life and social support are closely related. Efforts should be made to improve the social support system and the quality of life of the community elderly patients with chronic pain.