Abstract:Objective To study the feasibility and clinical efficacy of iRoot SP in the treatment of adult teeth with apical open. Methods Fifty adult teeth with both chronic apical periodontitis and apical open were selected in the Microscopic Root Canal Treatment Center of Stomatology Hospital in Jinzhou Medical University from January 2014 to October 2015. The teeth were randomly divided into 2 groups by the random number table: iRoot SP group with 25 cases, MTA group with 25 cases. The teeth in the iRoot SP group (experimental group) were filled with iRoot SP to the apex (4 mm thick), the teeth in the MTA group (control group) were filled with MTA to the apex (4 mm thick), the upper section of the root canal was filled by hot gutta-percha vertical condensation. The patients had routine follow-up in 6 and 12 months and X-rays were taken to observe the clinical efficacy. Results After treatment, all teeth did not have spontaneous pain or occlusion pain; there was no percussion pain or tenderness in clinical examination. The sinus disappeared, the gums turned to be normal. After 12 months the X-ray of the experimental group showed the apical shadow of 15 teeth disappeared, that of 8 teeth was reduced significantly,the shadow of 2 teeth did not change, the total effective rate was 92.0%. In the control group, X-ray showed the apical shadow of 17 teeth disappeared completely, that of 8 teeth significantly reduced, the total effective rate was 100.0%. Conclusions Through observation of the clinical efficacy of 43 patients, iRoot SP can be used for the adult tooth with the apical open, its short-term clinical efficacy is substantial, but the long-term clinical efficacy should be further observed.