Abstract:To analyze the mechanism of needle-knife therapy targeted at the posterior tubercles of cervical vertebral transverse processes for cervical spondylotic radiculopathy (CSR) from the view of anatomy. Methods Thirty -one CSR patients were laterally positioned. Needle -knife was targeted at the posterior tubercles of cervical vertebral transverse processes, and released the surrounding structures. The patients' symptoms, signs and X-ray changes of cervical vertebrae were reviewed 10 days after needle-knife treatment. The relationships between the surrounding structures of the posterior tubercles and the spinal nerve roots were observed after both sides of cervical vertibrae of the 6 adult cadavers were dissected. Results Ten days after needle-knife treatment, the symptoms of upper limb numbness and pain disappeared or obviously relieved in 83.9% of the patients; the negative rates of brachial plexus traction and intervertebral foramen extrusion test were 84.2% and 75.0% respectively; X-ray film displayed that the space between the transverse processes of cervical vertebrae and longitudinal diameter of external intervertebral foramen were widened by 5.24% and 15.87% respectively. Autopsy revealed that the posterior tubercles were located in the posterior-lateral side of the spinal nerve roots, the anterior and lateral sides of the posterior tubercles were mainly attached by scalenus medius, scalenus posterior and levator scapulae tendon. Part of the scalenus medius, scalenus posterior, levator scapulae tendon and scalenus anterior tendon originated from the anterior tubercles crossed the sulci nervi spinalis and merged into the posterior tubercles. There was an obvious ligament connection between the adjacent posterior tubercles. Conclusions The mechnism of needle-knife therapy for CRS targeted at posterior tubercles of cervical vertebral transverse processes may be due to relief of the compression of the nerve roots by the ligaments and tendons around the posterior tubercles.