Abstract:Objective To compare the effect of different treatment methods on wound healing of the relaxation incisions of palatorrhaphy. Methods A total of 184 patients receiving cleft palate surgery were selected and randomly divided into three groups. The bilateral relaxed incisions were treated with gelatin sponge in the group A,with biomedical fibrin glue in the group B, and with iodoform gauze in the group C. After operation, the recovery time, temperature, diet status, wound healing and bleeding etc were evaluated. Results There was no significant difference in each index between the group A and the group B (P > 0.05). There were significant differences in the rates of postoperative fever, hemorrhage and vomitting, the number of days of postoperative fever, the rates of mental recovery and food-intake recovery on the 1st day after operation, the scar width at loose incision, and the time of postoperative hospitalization among the 3 groups (P < 0.05). There was no significant difference in the incidence of postoperative infection, perforation or cleft recurrence among the three groups (P > 0.05). Conclusions Gelatin sponge and biomedical fibrin glue have good clinical application value in management of relaxed incisions with the advantages of good hemostasis, quick diet recovery and wound healing.