血液净化治疗对急性乌头碱中毒患者心律失常转复的影响

Effect of blood purification treatment on cardioversion of arrhythmia in patients with acute aconitine poisoning

摘要:

目的 探讨血液净化治疗对急性乌头碱类中毒患者心律失常转复的影响。方法 选取2009 年11 月-2017 年6 月就诊于浙江衢化医院急诊科的72 例急性乌头碱中毒心律失常患者为研究对象。随机分为对照组和观察组，对照组实施常规治疗方案，观察组在此基础上应用血液净化治疗。观察两组患者心律失常转复、中毒症状缓解及不良反应发生情况。结果 经过24 h 的治疗，观察组治疗总有效率为91.67%，高于对照组的72.22%（P <0.05）；观察组患者心率恢复正常时间和心律不齐消失时间较对照组短（P <0.05）；观察组患者肢体麻木、呕吐、心悸缓解时间及低血压恢复正常的时间较对照组短（P <0.05）；治疗过程中，观察组患者不良反应发生率为5.56%，低于对照组的33.33%（P <0.05）。结论 应用血液净化治疗急性乌头碱中毒心律失常患者，可以更快速地缓解患者症状，同时不良反应更少，临床疗效更好。

Abstract:

Objective To investigate the effect of blood purification treatment on cardioversion of arrhythmia in patients with acute aconitine poisoning. Methods Seventy-two patients with acute aconitine poisoning treated in our hospital from November 2009 to June 2017 were selected as the subjects. They were divided into control group and study group according to the random number table with 36 cases in each group. The control group was treated with conventional treatment, the observation group was treated with blood purification on the basis of conventional treatment. Arrhythmia cardioversion, relief of poisoning symptoms and adverse reactions of the two groups were observed. Results After treatment for 24 h, the total effective rate of the observation group was 91.67%, which was significantly higher than that (72.22%) of the control group (P < 0.05); the heart rate recovery time and arrhythmia disappearance time of the observation group were significantly shorter than those of the control group (P < 0.05);the remission time of limb numbness, vomiting, palpitation and the time of hypotension returning to normal in the observation group were significantly shorter than those in the control group (P < 0.05). In the course of treatment,the total incidence of adverse reactions in the observation group was 5.56%, which was lower than that (33.33%) in the control group (P < 0.05). Conclusions Using blood purification to treat acute aconitine poisoning patients with arrhythmia, the symptoms can be relieved more quickly, with fewer adverse reactions and better clinical efficacy.