B型脑尿钠肽检测及外科Apgar评分对阻塞性黄疸患者术后心脏主要不良事件的预测作用

Predict role of serum BNP level combined with surgical Apgar score system on postoperative major cardiac adverse events in obstructive jaundice patients

摘要:

目的  探讨B型脑尿钠肽检测（BNP）及术中Apgar评分对阻塞性黄疸患者术后心脏主要不良事件的预测作用。方法  检测41例行外科治疗的阻塞性黄疸患者手术前后BNP水平，并对术中情况进行外科Apgar评分，统计其术后出现心脏主要不良事件的情况与两者的关系。结果  阻塞性黄疸患者术前BNP水平较基线水平升高（P <0.05），术后随着心功能改善可出现明显下降，术前BNP水平高者术后出现心脏主要不良事件几率增加；术中Apgar评分较低者术后出现心脏主要不良事件几率增加。结论  血浆BNP水平及术中外科Apgar评分系统对阻塞性黄疸患者术后出现心脏主要不良事件具有较好的预测价值。

Abstract:

Objective To investigate the predictive effect of serum BNP level and surgical Apgar scoring system on postoperative major cardiac adverse events (MACE) in obstructive jaundice (OJ) patients. Methods Pre-and post-operative serum BNP level were detected, and the surgical Apgar score was calculated during the surgery in 41 patients with OJ. The relationship of BNP level and surgical Apgar score with MACE after surgrey was analysied. Results Higher serum BNP levels after operation in patients with OJ were observed (P < 0.05), and declined BNP level accompanied with improved cardiac function after operation was observed. High BNP level and low surgical Apgar score related to the increasing incidence of MACE after surgery. Conclusions Serum level of BNP and surgical Apgar scoring system have  good predictive value of MACE in patients with OJ after surgrey.