Abstract:Objective To compare and analyze the change of directory in the two edition of National Essential Medicine List (NEML) and "New Rural Cooperative" (NRC), and to promote the perfection of NRC directory of Yunnan province and provide a base reference for the list of drug docking. Methods Classification, quantity and the coincidence rate of chemical drugs and biological products in two kinds of directory were compared. Results There were differences in categories, classifications, subdivisions of different varieties changes in two kinds of directory. Conclusions The 2012 edition of NEML is more scientific in the classification, drug containing and disease coverage. But coincidence rate of two kinds of directory is low, which is not conducive to the cohesion and the health insurance policy.