三维超声多平面模式计数窦卵泡可靠度

Study on the reliability and counting time of the 3D ultrasound multi plane model for antral follicle count

摘要:

目的  对比经阴道三维超声多平面模式与二维超声在计数窦卵泡（AFC）方面的可靠度及计数时间。方法  以2012年10月-2015年4月在该院妇产科就诊或检查的妇女为受试对象，由两名经验丰富的工作人员独立以二维和三维模式进行AFC，对比其计数差异，计算相关系数及一致性限度，对比计数时间。结果  ①对3个不同年龄段受试者而言，两名观察者的计数结果差异无统计学意义（P >0.05），同一观测者以不同方法的计数结果也未见显著差异（P >0.05）；②不同观察者以同一方法行AFC所用时间差异无统计学意义（P > 0.05），但同一观察者以三维超声模式行AFC所需时间明显高于二维超声（P <0.01）；③两名观察者以三维超声多平面模式行AFC的差值范围与一致性限度范围更小，差值的均值更低，相关系数更高；④三维超声多平面模式对卵巢低反应性的诊断的准确度与敏感均更高。结论  三维超声多平面模式在行AFC时具有比二维超声更高的可靠度、一致性及准确度，虽其计数时间明显增加，但可大大缩短患者暴露的时间。

Abstract:

Objective To compare the reliability and counting time of the three dimensional ultrasound multi plane and two dimensional ultrasound in AFC. Methods Women came to our hospital's reproductive medical center for treatment or examination from Oct 2012 to Apr 2015 were chosen as subjects, antral follicle count were underwent by two experienced staff independently in 2D and 3D model. The two staffs' AFC differences and counting time were compared, and their correlation coefficient and the consistency of limit calculation were calculated. Results For three different ages, there was no significant difference between the results of two observers (P > 0.05), the results of a same observers in different methods also have no significant difference (P > 0.05); the counting time of a same way by different observers showed no significant difference, but the counting time of a same observer in 3D ultrasound mode was significantly higher than that of two-dimensional ultrasound (P < 0.01); In 3D ultrasound multiplanar mode, the two observers with difference range and consistency of the limits were smaller, mean difference was lower , while correlation coefficient was higher; In3D ultrasound multiplanar mode, the accuracy and sensitivity in diagnosis of ovarian flat low response were both higher. Conclusions In antral follicle counting, 3D ultrasonic multi plane model shows a higher reliability, consistency and accuracy than 2D ultrasound, although its counting time is obviously increased, but it can greatly shorten the time of exposure for subjects.